Hemolysis and Erythropoiesis

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Hemolysis and Erythropoiesis . VI . A Comparative

O UR PREVIOUS OBSERVATIONS have shown that intraperitoneal administration of autohemolysates accelerates the recovery from anemia in bled dogs.13 On the basis of this and other experimental data4#{176} we reconsidered the hypothesis7’8 that red cell constituents have an erythropoietic stimulatory effect.1’6 However, it has been suggested that the above findings are due, instead, to the availabi...

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Hemolysis and erythropoiesis. VI. A comparative study of the utilization of hemoglobin iron and transferrin iron by the erythropoietic tissue.

O UR PREVIOUS OBSERVATIONS have shown that intraperitoneal administration of autohemolysates accelerates the recovery from anemia in bled dogs.13 On the basis of this and other experimental data4#{176} we reconsidered the hypothesis7’8 that red cell constituents have an erythropoietic stimulatory effect.1’6 However, it has been suggested that the above findings are due, instead, to the availabi...

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Oxidative Hemolysis and Precipitation

The propensity of certain chemicals and drugs to induce hemolytic anemias has been a subject of much interest for almost a century (1-4). The majority of substances so active are aromatic compounds containing amino-, nitro-, or hydroxy groups, although a number of inorganic compounds (e.g., hydroxylamines, nitrates, nitrites and chlorates) are also active (1-4). Such compounds usually cause red...

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Erythropoiesis: development and differentiation.

Through their oxygen delivery function, red blood cells are pivotal to the healthy existence of all vertebrate organisms. These cells are required during all stages of life--embryonic, fetal, neonatal, adolescent, and adult. In the adult, red blood cells are the terminally differentiated end-product cells of a complex hierarchy of hematopoietic progenitors that become progressively restricted t...

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ژورنال

عنوان ژورنال: Blood

سال: 1963

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v21.5.586.586